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Signatures of Cysteine Oxidation on Muscle Structural and Contractile Proteins Are Associated with Physical Performance and Muscle Function in Older Adults: Study of Muscle, Mobility and Aging (SOMMA)

Oxidative stress is considered a contributor to declining muscle function and mobility during aging; however, the underlying molecular mechanisms remain poorly described. We hypothesized that greater levels of cysteine (Cys) oxidation on muscle proteins are associated with decreased measures of mobi...

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Detalles Bibliográficos
Autores principales: Day, Nicholas J., Kelly, Shane S., Lui, Li-Yung, Mansfield, Tyler A., Gaffrey, Matthew J., Trejo, Jesse B., Sagendorf, Tyler J., Attah, Kwame, Moore, Ronald J., Douglas, Collin M., Newman, Anne B., Kritchevsky, Stephen B., Kramer, Philip A., Marcinek, David J., Coen, Paul M., Goodpaster, Bret H., Hepple, Russell T., Cawthon, Peggy M., Petyuk, Vladislav A., Esser, Karyn A., Qian, Wei-Jun, Cummings, Steven R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659491/
https://www.ncbi.nlm.nih.gov/pubmed/37986748
http://dx.doi.org/10.1101/2023.11.07.23298224