Cargando…

Estimands for clinical endpoints in Tuberculosis treatment randomized controlled trials: a retrospective application in a completed trial

BACKGROUND: Randomized trials for the treatment of tuberculosis (TB) rely on a composite primary outcome to capture unfavorable treatment responses. However, variability between trials in the outcome definition and estimation methods complicates across-trial comparisons and hinders the advancement o...

Descripción completa

Detalles Bibliográficos
Autores principales: Weir, Isabelle R, Dufault, Suzanne M, Phillips, Patrick PJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659528/
https://www.ncbi.nlm.nih.gov/pubmed/37986887
http://dx.doi.org/10.21203/rs.3.rs-3486707/v1