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Estimands for clinical endpoints in Tuberculosis treatment randomized controlled trials: a retrospective application in a completed trial
BACKGROUND: Randomized trials for the treatment of tuberculosis (TB) rely on a composite primary outcome to capture unfavorable treatment responses. However, variability between trials in the outcome definition and estimation methods complicates across-trial comparisons and hinders the advancement o...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659528/ https://www.ncbi.nlm.nih.gov/pubmed/37986887 http://dx.doi.org/10.21203/rs.3.rs-3486707/v1 |