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Entorhinal cortex vulnerability to human APP expression promotes hyperexcitability and tau pathology

Preventative treatment for Alzheimer’s Disease is of dire importance, and yet, cellular mechanisms underlying early regional vulnerability in Alzheimer’s Disease remain unknown. In human patients with Alzheimer’s Disease, one of the earliest observed pathophysiological correlates to cognitive declin...

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Detalles Bibliográficos
Autores principales: Goettemoeller, Annie M, Banks, Emmie, McCann, Katharine E, Kumar, Prateek, South, Kelly, Olah, Viktor J, Ramelow, Christina C, Duong, Duc M, Seyfried, Nicholas T, Rangaraju, Srikant, Weinshenker, David, Rowan, Matthew JM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659529/
https://www.ncbi.nlm.nih.gov/pubmed/37987015
http://dx.doi.org/10.21203/rs.3.rs-3370607/v1