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Neuronal Glycogen Breakdown Mitigates Tauopathy via Pentose Phosphate Pathway-Mediated Oxidative Stress Reduction

Tauopathies encompass a range of neurodegenerative disorders, such as Alzheimer’s disease (AD) and frontotemporal dementia (FTD). Unfortunately, current treatment approaches for tauopathies have yielded limited success, underscoring the pressing need for novel therapeutic strategies. We observed dis...

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Detalles Bibliográficos
Autores principales: Bar, Sudipta, Wilson, Kenneth A., Hilsabeck, Tyler A.U., Alderfer, Sydney, Dammer, Eric B., Burton, Jordan B, Shah, Samah, Holtz, Anja, Carrera, Enrique M., Beck, Jennifer N., Chen, Jackson H, Kauwe, Grant, Tracy, Tara E., Seyfried, Nicholas T., Schilling, Birgit, Ellerby, Lisa M., Kapahi, Pankaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659530/
https://www.ncbi.nlm.nih.gov/pubmed/37986935
http://dx.doi.org/10.21203/rs.3.rs-3526342/v1