Genetically proxied HTRA1 protease activity and circulating levels independently predict risk of ischemic stroke and coronary artery disease

HTRA1 has emerged as a major risk gene for stroke and cerebral small vessel disease with both rare and common variants contributing to disease risk. However, the precise mechanisms mediating this risk remain largely unknown as does the full spectrum of phenotypes associated with genetic variation in...

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Detalles Bibliográficos
Autores principales: Dichgans, Martin, Malik, Rainer, Beaufort, Nathalie, Tanaka, Koki, Georgakis, Marios, He, Yunye, Koido, Masaru, Terao, Chikashi, Anderson, Christopher, Kamatani, Yoichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659557/
https://www.ncbi.nlm.nih.gov/pubmed/37986915
http://dx.doi.org/10.21203/rs.3.rs-3523612/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659557/
https://www.ncbi.nlm.nih.gov/pubmed/37986915
http://dx.doi.org/10.21203/rs.3.rs-3523612/v1

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