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Personalized statin treatment plan using counterfactual approach with multi-objective optimization over benefits and risks

BACKGROUND: Statins are a class of drugs that lower cholesterol levels in the blood by inhibiting an enzyme called 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase. High cholesterol levels can lead to plaque buildup in the arteries, which can cause Atherosclerotic Cardiovascular Disease(AS...

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Detalles Bibliográficos
Autores principales: Liang, Yue, Yew, Pui Ying, Loth, Matt, Adam, Terrence J., Wolfson, Julian, Tonellato, Peter J., Chi, Chin-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659576/
https://www.ncbi.nlm.nih.gov/pubmed/37986733
http://dx.doi.org/10.1016/j.imu.2023.101362