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Mechanism of stepwise electron transfer in six-transmembrane epithelial antigen of the prostate (STEAP) 1 and 2

Six transmembrane epithelial antigen of the prostate (STEAP) 1–4 are membrane-embedded hemoproteins that chelate a heme prosthetic group in a transmembrane domain (TMD). STEAP2–4, but not STEAP1, have an intracellular oxidoreductase domain (OxRD) and can mediate cross-membrane electron transfer from...

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Detalles Bibliográficos
Autores principales: Chen, Kehan, Wang, Lie, Shen, Jiemin, Tsai, Ah-Lim, Zhou, Ming, Wu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659578/
https://www.ncbi.nlm.nih.gov/pubmed/37983176
http://dx.doi.org/10.7554/eLife.88299