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The potential clinical impact of cell type‐specific genetic regulation: Crohn's disease

Complex diseases are heterogenous due to variation in their genetic and environmental underpinnings, leading to varied treatment responses. Genome‐wide association studies (GWAS) integrated with single‐cell expression quantitative trait loci analyses (eQTL) can pinpoint cell‐type specific candidate...

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Detalles Bibliográficos
Autores principales: Tyebally, Rika, Xue, Angli, Powell, Joseph E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659767/
https://www.ncbi.nlm.nih.gov/pubmed/37983917
http://dx.doi.org/10.1002/ctm2.1474