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The m(5)C methyltransferase NSUN2 promotes codon‐dependent oncogenic translation by stabilising tRNA in anaplastic thyroid cancer

BACKGROUND: Translation dysregulation plays a crucial role in tumourigenesis and cancer progression. Oncogenic translation relies on the stability and availability of tRNAs for protein synthesis, making them potential targets for cancer therapy. METHODS: This study performed immunohistochemistry ana...

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Detalles Bibliográficos
Autores principales: Li, Peng, Wang, Wenlong, Zhou, Ruixin, Ding, Ying, Li, Xinying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659772/
https://www.ncbi.nlm.nih.gov/pubmed/37983928
http://dx.doi.org/10.1002/ctm2.1466