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The m(5)C methyltransferase NSUN2 promotes codon‐dependent oncogenic translation by stabilising tRNA in anaplastic thyroid cancer
BACKGROUND: Translation dysregulation plays a crucial role in tumourigenesis and cancer progression. Oncogenic translation relies on the stability and availability of tRNAs for protein synthesis, making them potential targets for cancer therapy. METHODS: This study performed immunohistochemistry ana...
Autores principales: | Li, Peng, Wang, Wenlong, Zhou, Ruixin, Ding, Ying, Li, Xinying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659772/ https://www.ncbi.nlm.nih.gov/pubmed/37983928 http://dx.doi.org/10.1002/ctm2.1466 |
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