Phage display assisted discovery of a pH‐dependent anti‐α‐cobratoxin antibody from a natural variable domain library

Recycling IgG antibodies bind to their target antigen at physiological pH in the blood stream and release them upon endocytosis when pH levels drop, allowing the IgG antibodies to be recycled into circulation via FcRn‐mediated cellular pathways, while the antigens undergo lysosomal degradation. This...

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Detalles Bibliográficos
Autores principales: Tulika, Tulika, Pedersen, Rasmus W., Rimbault, Charlotte, Ahmadi, Shirin, Rivera‐de‐Torre, Esperanza, Fernández‐Quintero, Monica L., Loeffler, Johannes R., Bohn, Markus‐Frederik, Ljungars, Anne, Ledsgaard, Line, Voldborg, Bjørn G., Ruso‐Julve, Fulgencio, Andersen, Jan Terje, Laustsen, Andreas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659949/
https://www.ncbi.nlm.nih.gov/pubmed/37897425
http://dx.doi.org/10.1002/pro.4821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659949/
https://www.ncbi.nlm.nih.gov/pubmed/37897425
http://dx.doi.org/10.1002/pro.4821

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