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Mitochondrial injury during normothermic regional perfusion (NRP) and hypothermic oxygenated perfusion (HOPE) in a rodent model of DCD liver transplantation

BACKGROUND: Normothermic regional perfusion (NRP) and hypothermic-oxygenated-perfusion (HOPE), were both shown to improve outcomes after liver transplantation from donors after circulatory death (DCD). Comparative clinical and mechanistical studies are however lacking. METHODS: A rodent model of NRP...

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Detalles Bibliográficos
Autores principales: Panconesi, Rebecca, Carvalho, Mauricio Flores, Eden, Janina, Fazi, Marilena, Ansari, Fariha, Mancina, Leandro, Navari, Nadia, Sousa Da Silva, Richard Xavier, Dondossola, Daniele, Borrego, Lucia Bautista, Pietzke, Matthias, Peris, Adriano, Meierhofer, David, Muiesan, Paolo, Galkin, Alexander, Marra, Fabio, Dutkowski, Philipp, Schlegel, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10660010/
https://www.ncbi.nlm.nih.gov/pubmed/37924707
http://dx.doi.org/10.1016/j.ebiom.2023.104861