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Network pharmacology and in vitro experimental verification to reveal the mechanism of Astragaloside IV against kidney ischemia-reperfusion injury

Ischemic acute kidney injury (AKI) is a prevalent disorder among hospitalized patients worldwide. Astragaloside IV (AS-IV) has been shown to protect against ischemic AKI. However, the specific effects and mechanisms of AS-IV on alleviating kidney ischemia-reperfusion (I/R) injury remain unclear. The...

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Detalles Bibliográficos
Autores principales: Guo, Yan, Wang, Jinfu, Hua, Yanjie, Jiang, Mengya, Xu, Wanyue, Shi, Yanpeng, Yang, Jiehong, Wan, Haitong, Yang, Ruchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10660051/
https://www.ncbi.nlm.nih.gov/pubmed/38027853
http://dx.doi.org/10.1016/j.heliyon.2023.e21711