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Prognostic heterogeneity and clonal dynamics within distinct subgroups of myelodysplastic syndrome and acute myeloid leukemia with TP53 disruptions

TP53 aberrations constitute the highest risk subset of myelodysplastic neoplasms (MDS) and acute myeloid leukemia (AML). The International Consensus Classification questions the blast threshold between MDS and AML. In this study, we assess the distinction between MDS and AML for 76 patients with TP5...

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Detalles Bibliográficos
Autores principales: Patel, Shyam A., Cerny, Jan, Gerber, William K., Ramanathan, Muthalagu, Ediriwickrema, Asiri, Tanenbaum, Benjamin, Hutchinson, Lloyd, Meng, Xiuling, Flahive, Julie, Barton, Bruce, Gillis‐Smith, Andrew J., Suzuki, Sakiko, Khedr, Salwa, Selove, William, Higgins, Anne W., Miron, Patricia M., Simin, Karl, Woda, Bruce, Gerber, Jonathan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10660125/
https://www.ncbi.nlm.nih.gov/pubmed/38024632
http://dx.doi.org/10.1002/jha2.791