BRCA-mutated gastric adenocarcinomas are associated with chromosomal instability and responsiveness to platinum-based chemotherapy

BACKGROUND: Homologous recombination defect is an important biomarker of chemotherapy in certain tumor types, and the presence of pathogenic or likely pathogenic mutations involving BRCA1 or BRCA2 (p-BRCA) mutations is the most well-established marker for the homologous recombination defect. Gastric...

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Detalles Bibliográficos
Autores principales: Oh, Ji Hyun, Sung, Chang Ohk, Kim, Hyung-Don, Chun, Sung-Min, Kim, Jihun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Pathologists and the Korean Society for Cytopathology 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10660362/
https://www.ncbi.nlm.nih.gov/pubmed/37981726
http://dx.doi.org/10.4132/jptm.2023.10.22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10660362/
https://www.ncbi.nlm.nih.gov/pubmed/37981726
http://dx.doi.org/10.4132/jptm.2023.10.22

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