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Super-resolution microscopy reveals the nanoscale cluster architecture of the DEK protein cancer biomarker

DEK protein, a key chromatin regulator, is strongly overexpressed in various forms of cancer. While conventional microscopy revealed DEK as uniformly distributed within the cell nucleus, advanced super-resolution techniques uncovered cluster-like structures. However, a comprehensive understanding of...

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Detalles Bibliográficos
Autores principales: Pierzynska-Mach, Agnieszka, Diaspro, Alberto, Cella Zanacchi, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10660485/
https://www.ncbi.nlm.nih.gov/pubmed/38026229
http://dx.doi.org/10.1016/j.isci.2023.108277