GITR activation ex vivo impairs CD8 T cell function in people with HIV on antiretroviral therapy

Glucocorticoid-induced tumor necrosis factor related protein (GITR) is a co-stimulatory immune checkpoint molecule constitutively expressed on regulatory T cells (T(regs)) and on activated T conventional cells (T(conv)). In blood collected from PWH on suppressive ART, GITR expression was reduced in...

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Detalles Bibliográficos
Autores principales: Gubser, Céline, Pascoe, Rachel D., Chang, Judy, Chiu, Chris, Solomon, Ajantha, Cao, Rosalyn, Rasmussen, Thomas A., Lewin, Sharon R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10660494/
https://www.ncbi.nlm.nih.gov/pubmed/38026168
http://dx.doi.org/10.1016/j.isci.2023.108165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10660494/
https://www.ncbi.nlm.nih.gov/pubmed/38026168
http://dx.doi.org/10.1016/j.isci.2023.108165

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