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In Silico Design of a New Epitope-Based Vaccine against Grass Group 1 Allergens

HIGHLIGHTS: What are the main findings? A peptide consisting of 20 amino acids was designed in silico as a grass pollen allergy vaccine. The epitope-based vaccine has been validated by molecular docking analysis and ex vivo T-cell stimulation assay. It covers more than 80% of the European and global...

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Detalles Bibliográficos
Autores principales: Moten, Dzhemal, Batsalova, Tsvetelina, Apostolova, Desislava, Mladenova, Tsvetelina, Dzhambazov, Balik, Teneva, Ivanka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10660545/
https://www.ncbi.nlm.nih.gov/pubmed/37987298
http://dx.doi.org/10.3390/arm91060036