Synthesis and biochemical evaluation of 17-N-beta-aminoalkyl-4,5α-epoxynormorphinans

Opiate alkaloids and their synthetic derivatives are still widely used in pain management, drug addiction, and abuse. To avoid serious side effects, compounds with properly designed pharmacological profiles at the opioid receptor subtypes are long needed. Here a series of 17-N-substituted derivative...

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Detalles Bibliográficos
Autores principales: Ötvös, Ferenc, Szűcs, Edina, Urai, Ákos, Köteles, István, Szabó, Pál T., Varga, Zsuzsanna Katalin, Gombos, Dávid, Hosztafi, Sándor, Benyhe, Sándor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10660610/
https://www.ncbi.nlm.nih.gov/pubmed/37985681
http://dx.doi.org/10.1038/s41598-023-46317-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10660610/
https://www.ncbi.nlm.nih.gov/pubmed/37985681
http://dx.doi.org/10.1038/s41598-023-46317-3

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