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Berberine and aspirin prevent traumatic heterotopic ossification by inhibition of BMP signalling pathway and osteogenic differentiation

Heterotopic ossification (HO) is a pathological process that often occurs in soft tissues following severe trauma. There is no effective therapy for HO. The BMP signalling pathway plays an essential role in the pathogenesis of HO. Our previous study showed that AMPK negatively regulates the BMP sign...

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Detalles Bibliográficos
Autores principales: Fan, Jingjing, Gao, Jiayu, Chen, Jie, Hou, Jia, Liu, Mengchao, Dang, Yanmiao, Lin, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10660630/
https://www.ncbi.nlm.nih.gov/pubmed/37605888
http://dx.doi.org/10.1111/jcmm.17919