Development of a HPLC Method for Analysis of a Combination of Clofazimine, Isoniazid, Pyrazinamide, and Rifampicin Incorporated into a Dermal Self-Double-Emulsifying Drug Delivery System

We describe the development and validation of a new high performance liquid chromatography (HPLC) method for analysis of a combination of the first-line anti-tubercular drugs isoniazid, pyrazinamide, and rifampicin together with clofazimine. This is a unique challenge since clofazimine and rifampici...

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Detalles Bibliográficos
Autores principales: van Staden, Daniélle, Haynes, Richard K., Van der Kooy, Frank, Viljoen, Joe M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Technical Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10660689/
https://www.ncbi.nlm.nih.gov/pubmed/37987351
http://dx.doi.org/10.3390/mps6060104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10660689/
https://www.ncbi.nlm.nih.gov/pubmed/37987351
http://dx.doi.org/10.3390/mps6060104

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