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The Typical tRNA Co-Expresses Multiple 5′ tRNA Halves Whose Sequences and Abundances Depend on Isodecoder and Isoacceptor and Change with Tissue Type, Cell Type, and Disease

Transfer RNA-derived fragments (tRFs) are noncoding RNAs that arise from either mature transfer RNAs (tRNAs) or their precursors. One important category of tRFs comprises the tRNA halves, which are generated through cleavage at the anticodon. A given tRNA typically gives rise to several co-expressed...

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Detalles Bibliográficos
Autores principales: Akins, Robert Brian, Ostberg, Kayleigh, Cherlin, Tess, Tsiouplis, Nikolas J., Loher, Phillipe, Rigoutsos, Isidore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10660753/
https://www.ncbi.nlm.nih.gov/pubmed/37987365
http://dx.doi.org/10.3390/ncrna9060069