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Novel mitochondrial mechanisms of cognitive regulation in subjects with cognitive impairments

INTRODUCTION: Prior mechanistic studies in rodents showed decreased levels of the pivotal mitochondrial metabolite acetyl-L-carnitine (LAC) in relation to cognitive deficits and depressive-like behavior (Neuron 2017, 10.1016/j.neuron.2017.09.020, PNAS 2013, 10.1073/pnas.1216100110), providing the ba...

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Detalles Bibliográficos
Autores principales: Bigio, B., Lima-Filho, R., Barnhill, O., Sudo, F., Drummond, C., Assunção, N., Vanderborght, B., Tovar-Moll, F., Mattos, P., Ferreira, S., De Felice, F., Lourenco, M., Nasca, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10660875/
http://dx.doi.org/10.1192/j.eurpsy.2023.1274