How do pilot and feasibility studies inform randomised placebo-controlled trials in surgery? A systematic review

INTRODUCTION: Randomised controlled trials (RCTs) with a placebo comparator are considered the gold standard study design when evaluating healthcare interventions. These are challenging to design and deliver in surgery. Guidance recommends pilot and feasibility work to optimise main trial design and...

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Detalles Bibliográficos
Autores principales: Cousins, Sian, Gormley, Alexander, Chalmers, Katy, Campbell, Marion K, Beard, David J, Blencowe, Natalie S, Blazeby, Jane M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Surgery
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10660967/
https://www.ncbi.nlm.nih.gov/pubmed/37989384
http://dx.doi.org/10.1136/bmjopen-2022-071094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10660967/
https://www.ncbi.nlm.nih.gov/pubmed/37989384
http://dx.doi.org/10.1136/bmjopen-2022-071094

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