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Module-Based Polyketide Synthase Engineering for de Novo Polyketide Biosynthesis

[Image: see text] Polyketide retrobiosynthesis, where the biosynthetic pathway of a given polyketide can be reversibly engineered due to the colinearity of the polyketide synthase (PKS) structure and function, has the potential to produce millions of organic molecules. Mixing and matching modules fr...

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Detalles Bibliográficos
Autores principales: Nava, Alberto A., Roberts, Jacob, Haushalter, Robert W., Wang, Zilong, Keasling, Jay D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661043/
https://www.ncbi.nlm.nih.gov/pubmed/37871264
http://dx.doi.org/10.1021/acssynbio.3c00282