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Impact of Additives on Drug Particles during Liquid Antisolvent Crystallization and Subsequent Freeze-Drying

[Image: see text] The impact of single or combinations of additives on the generation of nanosuspensions of two poorly water-soluble active pharmaceutical ingredients (APIs), fenofibrate (FF) and dalcetrapib (DCP), and their isolation to the dry state via antisolvent (AS) crystallization followed by...

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Detalles Bibliográficos
Autores principales: Ghosh, Peuli, Rasmuson, Ake, Hudson, Sarah P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661054/
https://www.ncbi.nlm.nih.gov/pubmed/38025987
http://dx.doi.org/10.1021/acs.oprd.3c00204