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Conformational features and interaction mechanisms of V(H)H antibodies with β‐hairpin CDR3: A case of Nb8‐HigB2 interaction
The β‐hairpin conformation is regarded as an important basic motif to form and regulate protein–protein interactions. Single‐domain V(H)H antibodies are potential therapeutic and diagnostic tools, and the third complementarity‐determining regions of the heavy chains (CDR3s) of these antibodies are c...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661080/ https://www.ncbi.nlm.nih.gov/pubmed/37916305 http://dx.doi.org/10.1002/pro.4827 |