Cargando…

Cryopreservation of assay-ready hepatocyte monolayers by chemically-induced ice nucleation: preservation of hepatic function and hepatotoxicity screening capabilities

Cell culture plays a critical role in biomedical discovery and drug development. Primary hepatocytes and hepatocyte-derived cell lines are especially important cellular models for drug discovery and development. To enable high-throughput screening and ensure consistent cell phenotypes, there is a ne...

Descripción completa

Detalles Bibliográficos
Autores principales: Tomás, Ruben M. F., Dallman, Robert, Congdon, Thomas R., Gibson, Matthew I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661096/
https://www.ncbi.nlm.nih.gov/pubmed/37840476
http://dx.doi.org/10.1039/d3bm01046e