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Cryopreservation of assay-ready hepatocyte monolayers by chemically-induced ice nucleation: preservation of hepatic function and hepatotoxicity screening capabilities
Cell culture plays a critical role in biomedical discovery and drug development. Primary hepatocytes and hepatocyte-derived cell lines are especially important cellular models for drug discovery and development. To enable high-throughput screening and ensure consistent cell phenotypes, there is a ne...
Autores principales: | Tomás, Ruben M. F., Dallman, Robert, Congdon, Thomas R., Gibson, Matthew I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661096/ https://www.ncbi.nlm.nih.gov/pubmed/37840476 http://dx.doi.org/10.1039/d3bm01046e |
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