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O-GlcNAcylation regulates OTX2’s proteostasis

O-GlcNAcylation is a key post-translational modification, playing a vital role in cell signaling during development, especially in the brain. In this study, we investigated the role of O-GlcNAcylation in regulating the homeobox protein OTX2, which contributes to various brain disorders, such as comb...

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Detalles Bibliográficos
Autores principales: Wulff-Fuentes, Eugenia, Boakye, Jeffrey, Kroenke, Kaeley, Berendt, Rex R., Martinez-Morant, Carla, Pereckas, Michaela, Hanover, John A., Olivier-Van Stichelen, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661118/
https://www.ncbi.nlm.nih.gov/pubmed/38026167
http://dx.doi.org/10.1016/j.isci.2023.108184