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Non-steroidal mineralocorticoid receptor antagonist finerenone ameliorates mitochondrial dysfunction via PI3K/Akt/eNOS signaling pathway in diabetic tubulopathy

Diabetic tubulopathy (DT) is a recently recognized key pathology of diabetic kidney disease (DKD). The mitochondria-centric view of DT is emerging as a vital pathological factor in different types of metabolic diseases, such as DKD. Finerenone (FIN), a novel non-steroidal mineralocorticoid receptor...

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Detalles Bibliográficos
Autores principales: Yao, Lan, Liang, Xianhui, Liu, Yamin, Li, Bingyu, Hong, Mei, Wang, Xin, Chen, Bohan, Liu, Zhangsuo, Wang, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661120/
https://www.ncbi.nlm.nih.gov/pubmed/37924663
http://dx.doi.org/10.1016/j.redox.2023.102946