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Magnesium-containing bioceramics stimulate exosomal miR-196a-5p secretion to promote senescent osteogenesis through targeting Hoxa7/MAPK signaling axis

Stem cell senescence is characterized by progressive functional dysfunction and secretory phenotypic changes including decreased proliferation, dysfunction of osteogenic and angiogenic differentiation, increased secretion of the senescence-associated secretory phenotype (SASP), which bring difficult...

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Detalles Bibliográficos
Autores principales: Qi, Lei, Fang, Xin, Yan, Jinge, Pan, Cancan, Ge, Weiwen, Wang, Jing, Shen, Steve GF., Lin, Kaili, Zhang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661166/
https://www.ncbi.nlm.nih.gov/pubmed/38024235
http://dx.doi.org/10.1016/j.bioactmat.2023.10.024