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Benefits of FAIMS to Improve the Proteome Coverage of Deteriorated and/or Cross-Linked TMT 10-Plex FFPE Tissue and Plasma-Derived Exosomes Samples

The proteome characterization of complex, deteriorated, or cross-linked protein mixtures as paired clinical FFPE or exosome samples isolated from low plasma volumes (250 µL) might be a challenge. In this work, we aimed at investigating the benefits of FAIMS technology coupled to the Orbitrap Explori...

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Detalles Bibliográficos
Autores principales: Montero-Calle, Ana, Garranzo-Asensio, María, Rejas-González, Raquel, Feliu, Jaime, Mendiola, Marta, Peláez-García, Alberto, Barderas, Rodrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661291/
https://www.ncbi.nlm.nih.gov/pubmed/37987315
http://dx.doi.org/10.3390/proteomes11040035