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Benefits of FAIMS to Improve the Proteome Coverage of Deteriorated and/or Cross-Linked TMT 10-Plex FFPE Tissue and Plasma-Derived Exosomes Samples
The proteome characterization of complex, deteriorated, or cross-linked protein mixtures as paired clinical FFPE or exosome samples isolated from low plasma volumes (250 µL) might be a challenge. In this work, we aimed at investigating the benefits of FAIMS technology coupled to the Orbitrap Explori...
Autores principales: | Montero-Calle, Ana, Garranzo-Asensio, María, Rejas-González, Raquel, Feliu, Jaime, Mendiola, Marta, Peláez-García, Alberto, Barderas, Rodrigo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661291/ https://www.ncbi.nlm.nih.gov/pubmed/37987315 http://dx.doi.org/10.3390/proteomes11040035 |
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