Can proline dehydrogenase—a key enzyme involved in proline metabolism—be a novel target for cancer therapy?

Emerging evidence suggests that proline metabolism is important for regulating the survival and death of different types of cancer cells. Proline dehydrogenase (PRODH), an enzyme catalyzing proline catabolism, and the degradation products of proline by PRODH, such as ATP and ROS, are known to play c...

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Detalles Bibliográficos
Autores principales: Xu, Xiangyuan, Zhang, Guangtao, Chen, Yijia, Xu, Weina, Liu, Yujing, Ji, Guang, Xu, Hanchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661406/
https://www.ncbi.nlm.nih.gov/pubmed/38023181
http://dx.doi.org/10.3389/fonc.2023.1254439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661406/
https://www.ncbi.nlm.nih.gov/pubmed/38023181
http://dx.doi.org/10.3389/fonc.2023.1254439

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