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Can proline dehydrogenase—a key enzyme involved in proline metabolism—be a novel target for cancer therapy?
Emerging evidence suggests that proline metabolism is important for regulating the survival and death of different types of cancer cells. Proline dehydrogenase (PRODH), an enzyme catalyzing proline catabolism, and the degradation products of proline by PRODH, such as ATP and ROS, are known to play c...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661406/ https://www.ncbi.nlm.nih.gov/pubmed/38023181 http://dx.doi.org/10.3389/fonc.2023.1254439 |