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Nitazoxanide and quercetin co-loaded nanotransfersomal gel for topical treatment of cutaneous leishmaniasis with macrophage targeting and enhanced anti-leishmanial effect

PURPOSE: Anti-leishmanial medications administered by oral and parenteral routes are less effective for treatment of cutaneous leishmaniasis (CL) and cause toxicity, hence targeted drug delivery is an efficient way to improve drug availability for CL with reduced toxicity. This study aimed to develo...

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Detalles Bibliográficos
Autores principales: Bashir, Sidra, Shabbir, Kanwal, Din, Fakhar ud, Khan, Saif Ullah, Ali, Zakir, Khan, Barkat Ali, Kim, Dong Wuk, Khan, Gul Majid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661431/
https://www.ncbi.nlm.nih.gov/pubmed/38027656
http://dx.doi.org/10.1016/j.heliyon.2023.e21939