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Preclinical long-term safety of intraspinal transplantation of human dorsal spinal GABA neural progenitor cells

Human pluripotent stem cell (hPSC)-derived neurons have shown promise in treating spinal cord injury (SCI). We previously showed that hPSC-derived dorsal spinal γ-aminobutyric acid (GABA) neurons can alleviate spasticity and promote locomotion in rats with SCI, but their long-term safety remains elu...

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Detalles Bibliográficos
Autores principales: Zheng, Xiaolong, Liu, Zhixian, He, Ziyu, Xu, Jia, Wang, YaNan, Gong, ChenZi, Zhang, Ruoying, Zhang, Su-Chun, Chen, Hong, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661464/
https://www.ncbi.nlm.nih.gov/pubmed/38026209
http://dx.doi.org/10.1016/j.isci.2023.108306