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Engineered deaminases as a key component of DNA and RNA editing tools

Over recent years, zinc-dependent deaminases have attracted increasing interest as key components of nucleic acid editing tools that can generate point mutations at specific sites in either DNA or RNA by combining a targeting module (such as a catalytically impaired CRISPR-Cas component) and an effe...

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Detalles Bibliográficos
Autores principales: Budzko, Lucyna, Hoffa-Sobiech, Karolina, Jackowiak, Paulina, Figlerowicz, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661471/
https://www.ncbi.nlm.nih.gov/pubmed/38028200
http://dx.doi.org/10.1016/j.omtn.2023.102062