Development of [(89)Zr]Zr-hCD103.Fab01A and [(68)Ga]Ga-hCD103.Fab01A for PET imaging to noninvasively assess cancer reactive T cell infiltration: Fab-based CD103 immunoPET

BACKGROUND: CD103 is an integrin specifically expressed on the surface of cancer-reactive T cells. The number of CD103+ T cells significantly increases during successful immunotherapy and might therefore be an attractive biomarker for noninvasive PET imaging of immunotherapy response. Since the long...

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Detalles Bibliográficos
Autores principales: Fan, Xiaoyu, Ważyńska, Marta A., Kol, Arjan, Perujo Holland, Noemi, Fernandes, Bruna, van Duijnhoven, Sander M. J., Plat, Annechien, van Eenennaam, Hans, Elsinga, Philip H., Nijman, Hans W., de Bruyn, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661679/
https://www.ncbi.nlm.nih.gov/pubmed/37985555
http://dx.doi.org/10.1186/s13550-023-01043-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661679/
https://www.ncbi.nlm.nih.gov/pubmed/37985555
http://dx.doi.org/10.1186/s13550-023-01043-9

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