Binding interactions of hydrophobically-modified flavonols with β-glucosidase: fluorescence spectroscopy and molecular modelling study

Natural flavonoids are capable of inhibiting glucosidase activity, so they can be used for treating diabetes mellitus and hypertension. However, molecular-level details of their interactions with glucosidase enzymes remain poorly understood. This paper describes the synthesis and spectral characteri...

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Detalles Bibliográficos
Autores principales: Chepeleva, Liudmyla V., Demidov, Oleksii O., Snizhko, Arsenii D., Tarasenko, Dmytro O., Chumak, Andrii Y., Kolomoitsev, Oleksii O., Kotliar, Volodymyr M., Gladkov, Eugene S., Kyrychenko, Alexander, Roshal, Alexander D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661682/
https://www.ncbi.nlm.nih.gov/pubmed/38020002
http://dx.doi.org/10.1039/d3ra06276g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661682/
https://www.ncbi.nlm.nih.gov/pubmed/38020002
http://dx.doi.org/10.1039/d3ra06276g

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