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Binding interactions of hydrophobically-modified flavonols with β-glucosidase: fluorescence spectroscopy and molecular modelling study
Natural flavonoids are capable of inhibiting glucosidase activity, so they can be used for treating diabetes mellitus and hypertension. However, molecular-level details of their interactions with glucosidase enzymes remain poorly understood. This paper describes the synthesis and spectral characteri...
Autores principales: | Chepeleva, Liudmyla V., Demidov, Oleksii O., Snizhko, Arsenii D., Tarasenko, Dmytro O., Chumak, Andrii Y., Kolomoitsev, Oleksii O., Kotliar, Volodymyr M., Gladkov, Eugene S., Kyrychenko, Alexander, Roshal, Alexander D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661682/ https://www.ncbi.nlm.nih.gov/pubmed/38020002 http://dx.doi.org/10.1039/d3ra06276g |
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