Functional Relevance of CTLA4 Variants: an Upgraded Approach to Assess CTLA4-Dependent Transendocytosis by Flow Cytometry

Variants of uncertain significance (VUS) in CTLA4 are frequently identified in patients with antibody deficiency or immune dysregulation syndromes including, but not limited to, patients with multi-organ autoimmunity and autoinflammation. However, to ascertain the diagnosis of CTLA4 insufficiency, t...

Descripción completa

Detalles Bibliográficos
Autores principales: Rojas-Restrepo, Jessica, Sindram, Elena, Zenke, Simon, Haberstroh, Hanna, Mitsuiki, Noriko, Gabrysch, Annemarie, Huebscher, Katrin, Posadas-Cantera, Sara, Krausz, Máté, Kobbe, Robin, Rohr, Jan C., Grimbacher, Bodo, Gámez-Díaz, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661720/
https://www.ncbi.nlm.nih.gov/pubmed/37740092
http://dx.doi.org/10.1007/s10875-023-01582-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661720/
https://www.ncbi.nlm.nih.gov/pubmed/37740092
http://dx.doi.org/10.1007/s10875-023-01582-9

Ejemplares similares