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Cytochrome P450-2D6 activity in people with codeine use disorder

Compound-analgesics containing codeine (CACC) have been a common source of codeine for people seeking opioid replacement therapy (ORT) for codeine use disorder (CUD). Our previous work demonstrated no relationship between pre-treatment CACC and ORT buprenorphine doses; we hypothesised that CYP2D6 ac...

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Detalles Bibliográficos
Autores principales: Daglish, Mark R. C., Reilly, Sarah R., Mostafa, Sam, Edwards, Cameron, O’Gorman, Thomas M., Hayllar, Jeremy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661737/
https://www.ncbi.nlm.nih.gov/pubmed/37940651
http://dx.doi.org/10.1038/s41397-023-00319-6