Validation of Anti-Adeno Associated Virus Serotype rh10 (AAVrh.10) Total and Neutralizing Antibody Immunogenicity Assays

Immunogenicity assessment of Adeno-Associated Virus (AAV) vectors is a critical part of gene therapy drug development. Whether the assays are used for inclusion/exclusion criteria or to monitor the safety and efficacy of the gene therapy, they are critical bioanalytical assessments. While total anti...

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Detalles Bibliográficos
Autores principales: Butala-Flores, Elizabeth, Nguyen, Thien, Selvan, Nithya, Armstrong, Luke, Miller, Michelle, Kamen, Lynn, Lester, Todd, Wernyj, Roman, Khanna, Richie, McNally, Jim, Hays, Amanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661749/
https://www.ncbi.nlm.nih.gov/pubmed/37880551
http://dx.doi.org/10.1007/s11095-023-03625-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661749/
https://www.ncbi.nlm.nih.gov/pubmed/37880551
http://dx.doi.org/10.1007/s11095-023-03625-7

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