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Mitragynine inhibits hippocampus neuroplasticity and its molecular mechanism

BACKGROUND: Mitragynine (MIT), the primary indole alkaloid of kratom (Mitragyna speciosa), has been associated with addictive and cognitive decline potentials. In acute studies, MIT decreases spatial memory and inhibits hippocampal synaptic transmission in long-term potentiation (LTP). This study in...

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Detalles Bibliográficos
Autores principales: Yunusa, Suleiman, Hassan, Zurina, Müller, Christian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661785/
https://www.ncbi.nlm.nih.gov/pubmed/37924443
http://dx.doi.org/10.1007/s43440-023-00541-w