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Ethanol deprivation and central 5-HT deficiency differentially affect the mRNA editing of the 5-HT(2C) receptor in the mouse brain

BACKGROUND: Serotonin (5-HT) 5-HT(2C) receptor mRNA editing (at five sites, A–E), implicated in neuropsychiatric disorders, including clinical depression, remains unexplored during alcohol abstinence—often accompanied by depressive symptoms. METHODS: We used deep sequencing to investigate 5-HT(2C) r...

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Detalles Bibliográficos
Autores principales: Zaniewska, Magdalena, Alenina, Natalia, Fröhler, Sebastian, Chen, Wei, Bader, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661786/
https://www.ncbi.nlm.nih.gov/pubmed/37923824
http://dx.doi.org/10.1007/s43440-023-00545-6