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Anti-inflammatory, Anti-fibrotic and Pro-cardiomyogenic Effects of Genetically Engineered Extracellular Vesicles Enriched in miR-1 and miR-199a on Human Cardiac Fibroblasts

RATIONALE: Emerging evidence indicates that stem cell (SC)- derived extracellular vesicles (EVs) carrying bioactive miRNAs are able to repair damaged or infarcted myocardium and ameliorate adverse remodeling. Fibroblasts represent a major cell population responsible for scar formation in the damaged...

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Detalles Bibliográficos
Autores principales: Kmiotek-Wasylewska, Katarzyna, Bobis-Wozowicz, Sylwia, Karnas, Elżbieta, Orpel, Monika, Woźnicka, Olga, Madeja, Zbigniew, Dawn, Buddhadeb, Zuba-Surma, Ewa K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661813/
https://www.ncbi.nlm.nih.gov/pubmed/37700183
http://dx.doi.org/10.1007/s12015-023-10621-2