Cargando…

Anti-inflammatory, Anti-fibrotic and Pro-cardiomyogenic Effects of Genetically Engineered Extracellular Vesicles Enriched in miR-1 and miR-199a on Human Cardiac Fibroblasts

RATIONALE: Emerging evidence indicates that stem cell (SC)- derived extracellular vesicles (EVs) carrying bioactive miRNAs are able to repair damaged or infarcted myocardium and ameliorate adverse remodeling. Fibroblasts represent a major cell population responsible for scar formation in the damaged...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kmiotek-Wasylewska, Katarzyna, Bobis-Wozowicz, Sylwia, Karnas, Elżbieta, Orpel, Monika, Woźnicka, Olga, Madeja, Zbigniew, Dawn, Buddhadeb, Zuba-Surma, Ewa K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661813/ https://www.ncbi.nlm.nih.gov/pubmed/37700183 http://dx.doi.org/10.1007/s12015-023-10621-2

Ejemplares similares

Extracellular vesicles from human iPSCs enhance reconstitution capacity of cord blood-derived hematopoietic stem and progenitor cells
por: Karnas, Elżbieta, et al.
Publicado: (2021)

Hypoxia enhances anti-fibrotic properties of extracellular vesicles derived from hiPSCs via the miR302b-3p/TGFβ/SMAD2 axis
por: Paw, Milena, et al.
Publicado: (2023)

Diverse impact of xeno-free conditions on biological and regenerative properties of hUC-MSCs and their extracellular vesicles
por: Bobis-Wozowicz, Sylwia, et al.
Publicado: (2016)

Anti-Tumor Activity of a miR-199-dependent Oncolytic Adenovirus
por: Callegari, Elisa, et al.
Publicado: (2013)

Association of H-Type Hypertension with miR-21, miR-29, and miR-199 in Kazahks of Xinjiang, China
por: He, Xin, et al.
Publicado: (2022)

miR-199a and miR-199b facilitate diffuse gastric cancer progression by targeting Frizzled-6
por: Hong, Soon Auck, et al.
Publicado: (2023)

Roles and Mechanism of miR-199a and miR-125b in Tumor Angiogenesis
por: He, Jun, et al.
Publicado: (2013)

Identification of New Rat Bone Marrow-Derived Population of Very Small Stem Cell with Oct-4A and Nanog Expression by Flow Cytometric Platforms
por: Labedz-Maslowska, Anna, et al.
Publicado: (2016)

Expression of MiR-140 and MiR-199 in Synovia and its Correlation with the Progression of Knee Osteoarthritis
por: Chao, Yu, et al.
Publicado: (2020)

The cardioprotective and anti-inflammatory effect of inhaled nitric oxide during Fontan surgery in patients with single ventricle congenital heart defects: a prospective randomized study
por: Kolcz, Jacek, et al.
Publicado: (2022)

Effect of TGF-β/smad signaling pathway blocking on expression profiles of miR-335, miR-150, miR-194, miR-27a, and miR-199a of hepatic stellate cells (HSCs)
por: Davoodian, Parivash, et al.
Publicado: (2017)

Serum and Extracellular Vesicle MicroRNAs miR-423, miR-199, and miR-93* As Biomarkers for Acute Graft-versus-Host Disease
por: Crossland, Rachel E., et al.
Publicado: (2017)

Antileukemic Effects of Anti-miR-146a, Anti-miR-155, Anti-miR-181a, and Prednisolone on Childhood Acute Lymphoblastic Leukemia
por: Durmaz, Burak, et al.
Publicado: (2021)

Circulating miR-26a-1, miR-146a and miR-199a-1 are potential candidate biomarkers for acute myocardial infarction
por: Xue, Sheng, et al.
Publicado: (2019)

A Description of the Hemolytic Component in Sickle Leg Ulcer: The Role of Circulating miR-199a-5p, miR-144, and miR-126
por: Santos, Edvan do Carmo, et al.
Publicado: (2022)

Diverging targets mediate the pathological roleof miR-199a-5p and miR-199a-3p by promoting cardiac hypertrophy and fibrosis
por: Zeng, Ni, et al.
Publicado: (2021)

MiR-195 enhances cardiomyogenic differentiation of the proepicardium/septum transversum by Smurf1 and Foxp1 modulation
por: Dueñas, Angel, et al.
Publicado: (2020)

Deregulation of miR-100, miR-99a and miR-199b in tissues and plasma coexists with increased expression of mTOR kinase in endometrioid endometrial carcinoma
por: Torres, Anna, et al.
Publicado: (2012)

miR-199a-3p increases the anti-tumor activity of palbociclib in liver cancer models
por: Callegari, Elisa, et al.
Publicado: (2022)

miR-199a-3p increases the anti-tumor activity of palbociclib in liver cancer models
por: Callegari, Elisa, et al.
Publicado: (2022)

miR-122 and miR-199 synergistically promote autophagy in oral lichen planus by targeting the Akt/mTOR pathway
por: Wang, Liang, et al.
Publicado: (2019)

Serum miR-34a-5p and miR-199a-3p as new biomarkers of neonatal sepsis
por: Abdelaleem, Omayma O., et al.
Publicado: (2022)

Circulating miR-627-5p and miR-199a-5p are promising diagnostic biomarkers of colorectal neoplasia
por: Zhao, Dong-Yan, et al.
Publicado: (2022)

miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer
por: Su, S-F, et al.
Publicado: (2013)

Lymph node or perineural invasion is associated with low miR-15a, miR-34c and miR-199b levels in head and neck squamous cell carcinoma
por: Sousa, Lucas O., et al.
Publicado: (2016)

Diagnostic and prognostic potential of serum miR-7, miR-16, miR-25, miR-93, miR-182, miR-376a and miR-429 in ovarian cancer patients
por: Meng, Xiaodan, et al.
Publicado: (2015)

Simultaneous downregulation of miR-21 and upregulation of miR-7 has anti-tumor efficacy
por: Bhere, Deepak, et al.
Publicado: (2020)

Identification of miR-199-5p and miR-199-3p Target Genes: Paxillin Facilities Cancer Cell Aggressiveness in Head and Neck Squamous Cell Carcinoma
por: Tanaka, Nozomi, et al.
Publicado: (2021)

Serum Level of miR-1 and miR-155 as Potential Biomarkers of Stress-Resilience of NET-KO and SWR/J Mice
por: Solich, Joanna, et al.
Publicado: (2020)

miR-1, miR-10b, miR-155, and miR-191 are novel regulators of BDNF
por: Varendi, Kärt, et al.
Publicado: (2014)

Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients
por: Qiu, Shuwei, et al.
Publicado: (2013)

Clinical relevance of microRNA miR-21, miR-31, miR-92a, miR-101, miR-106a and miR-145 in colorectal cancer
por: Schee, Kristina, et al.
Publicado: (2012)

Identification of miR-199a-5p, miR-214-3p and miR-99b-5p as Fibrosis-Specific Extracellular Biomarkers and Promoters of HSC Activation
por: Messner, Catherine Jane, et al.
Publicado: (2021)

Monocyte Chemoattractant Protein-Induced Protein 1 (MCPIP1) Enhances Angiogenic and Cardiomyogenic Potential of Murine Bone Marrow-Derived Mesenchymal Stem Cells
por: Labedz-Maslowska, Anna, et al.
Publicado: (2015)

The Progression of Liver Fibrosis Is Related with Overexpression of the miR-199 and 200 Families
por: Murakami, Yoshiki, et al.
Publicado: (2011)

Up-Regulation of miR-21, miR-25, miR-93, and miR-106b in Gastric Cancer
por: Larki, Pegah, et al.
Publicado: (2018)

Serum levels of miR-29, miR-122, miR-155 and miR-192 are elevated in patients with cholangiocarcinoma
por: Loosen, Sven H., et al.
Publicado: (2019)

Alpha-1 antitrypsin augmentation therapy decreases miR-199a-5p, miR-598 and miR-320a expression in monocytes via inhibition of NFκB
por: Hassan, Tidi, et al.
Publicado: (2017)

Human Papillomavirus 16 Oncoproteins Downregulate the Expression of miR-148a-3p, miR-190a-5p, and miR-199b-5p in Cervical Cancer
por: Han, Mi-Soon, et al.
Publicado: (2018)

Microvesicle-associated and circulating microRNAs in diabetic dyslipidemia: miR-218, miR-132, miR-143, and miR-21, miR-122, miR-155 have biomarker potential
por: Nemecz, Miruna, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_45t7itbut7evc5ossnq60tk2df