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Compromised diabetic heart function is not affected by miR-378a upregulation upon hyperglycemia

BACKGROUND: Cardiac-abundant microRNA-378a (miR-378a) is associated with postnatal repression of insulin–like growth factor 1 receptor (IGF-1R) controlling physiological hypertrophy and survival pathways. IGF-1/IGF-1R axis has been proposed as a therapeutic candidate against the pathophysiological p...

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Detalles Bibliográficos
Autores principales: Florczyk-Soluch, Urszula, Polak, Katarzyna, Sabo, Reece, Martyniak, Alicja, Stępniewski, Jacek, Dulak, Józef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661816/
https://www.ncbi.nlm.nih.gov/pubmed/37851320
http://dx.doi.org/10.1007/s43440-023-00535-8